منابع مشابه
Mutagenesis-generated mouse models of human infertility with abnormal sperm.
BACKGROUND The aetiology of human male fertility, with impairment of sperm number, motility and morphology (oligoasthenoteratozoospermia), has been difficult to understand, partly for lack of animal models. METHODS An ethylnitrosourea (ENU) mutagenesis strategy has been successful in producing heritable gene mutations with phenotypes similar to human male infertility, and here, we describe th...
متن کاملAbnormal sperm morphology
Sperm morphology is unique among the known cells and 3 major parts can be immediately distinguished: head, midpiece and tail. Normal sperm exhibit an oval-shaped head with a regular outline and a cap (acrosome) covering more than one-third of the head surface. The midpiece is slender, less than one third of the width of the head, straight and regular in outline. The tail is slender, uncoiled an...
متن کاملTransformation of sperm nuclei to metaphase chromosomes in the cytoplasm of maturing oocytes of the mouse
Zona-free oocytes of the mouse were inseminated at prometaphase I or metaphase I of meiotic maturation in vitro, and the behavior of the sperm nuclei within the oocyte cytoplasm was examined. If the oocytes were penetrated by up to three sperm, maturation continued during subsequent incubation and became arrested at metaphase II. Meanwhile, each sperm nucleus underwent the following changes. Fi...
متن کاملSurvey Sperm Parameter of Mouse Treated With Corn Oil
Purpose: The purpose of this study was to evaluated the effect of corn oil on mouse sperm count, motility, viability, quality of chromosome, testicular spermatid number per gram testis (TSN), anddaily sperm production (DSP). Materials and Methods: The protocol for corn oil adminstration was that male NMRI mice (the age groupe of 4weeks) received 100 and 150 ml corn oil orally for 14 days. The ...
متن کاملP-226: American Ginseng Effects on Damage Induced by Cyclophosphamide in The Nuclei of Rat Sperm
Background: Oxidative stress occurs when the oxidative homeostasis is damage. Excessive ROS are generated and this reaction has been proposed to produce marked damage to the structure and function of sperm. Materials and Methods: This study was designed to investigate the protective effects of of American Ginseng against cyclophosphamide - induced damage in the rat sperm. For this experiment, t...
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ژورنال
عنوان ژورنال: Reproduction
سال: 1992
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0960025